Saturday, February 16, 2013

2/16/2013 - Cletus' Necropsy (Autopsy) Results

2/16/13 - Cletus' necropsy (autopsy) came back the other day and the conclusion, to everyone's surprise was not, in fact schizencephaly, but rather porencephaly. 

I spoke with Cletus' neurologist at the University of Florida and the difference between schizencephaly and porencephaly is all grey matter lining the opening with schizencephaly and some white matter lining the opening with porencephaly.  Animals, including dogs have been known to have porencephaly although Cletus' case was pretty severe.

I asked about the CT Scan which was performed by this same doctor and other doctors where they "confirmed" the schizencephaly and the response was that it is truly impossible to know if it is porencephaly or schizencephaly until an autopsy is completed.

I then asked if we knew of his true diagnosis, would the treatment have been any different, could there have been anything we could have done to help Cletus that we did not do?  I was told no, we did everything we could possibly do and his treatment would not have been different.

What I am upset about is that I wrote to his neurologist back on February 3rd of 2012 bringing up porencephaly as a possible diagnosis for Cletus reather than schizencephaly. 

This is what I wrote (email dated February 3, 2012):

"...In addition, I have been doing research (as always) and have come across porencephaly as a possible alterior diagnosis for Cletus which I would like for your team to look into. Not that I disagree with the schizencephaly diagnosis, just that it is possible that porencephaly could be confused with schizencephaly at times."

And here is the neurosurgeon's response (email also dated February 3, 2012):

"...Porencephaly is just a hole in the cerebrum and there is generally normal brain tissue on all sides of the defect. Porencephaly isn’t really a diagnosis per se, it is the result of a local death of brain tissue; e.g. it is a just a descriptor of a gross anatomic lesion. The causes seen in veterinary medicine are generally viral infections in utero. Skull malformations are not generally a feature of porencephaly either."

They then performed the CT Scan on February 6th, 2012 and confirmed their diagnosis of schizencephaly. 

Part of my thinks the University was looking to make a "unique" diagnosis so they could write a paper which now they are not going to write because their diagnosis is proved wrong.  I just hope they did not cause Cletus any harm in doing so.

Love to all,

Doug

3 comments:

Gayle said...

Oh Doug,

This is so heartbreaking. AS began to read through and before I got to the part of you beginning to question the difference bewteen S and P, I began to think the exact smae thing. Then I went on to read your thoughts/questions and like you, my only concern is that nothing of what the UF Clinic did was of harm to your beautiful dog-son. I hae to believe it wasn't as i cannot handle the alternative. One of my rabbit-daughters left this evening @ 8:30p. The pain is immense. Gayle

Douglas Silber said...

I am sorry to hear about your rabbit Gayle. I am sure the time she had with you here on earth was filled with happiness and love and that is the best gift we could give to those we care for and care about. My condolences and thoughts are with you. Doug

Wake said...

Hi Douglas,

My name is Matt-- my girlfriends dog (Sadie) was diagnosed with Porencephaly (after repeated and regular seizures) and I am wondering if you know anything more about it? I'm trying to find information about the disorder, to see if we can help the puppy. The neurologist thinks we should put in a shunt to help brain fluid drain, but this is a very expensive procedure and may not work! I am hoping to find out as much as we can about this disorder, in the hopes we can make Sadie's life happy, healthy, and as long as possible! If you get this, please e-mail (replace the dash with an at sign) matthettich-gmail .

Thanks,
Matt Hettich